The progress in natural sciences and technological advancement has provided tremendous benefits and comforts to human society. Spirituality brings value to one’s existence and it provides answers to the fundamental questions that bother inquisitive minds. From a distance, science and spirituality may appear contradictory, and while pursuing a career in one, the practice Of the Other may appear an impediment. But, on delving deeper, as many of our founding fathers of science experienced, one would find that science and spirituality complement each other. They are methodologies to understand the various facets of the Absolute Truth. Science helps in spiritual realization. Spirituality helps in proper scientific understanding and a balanced world-view. With a scientific outlook, a spiritualist serves the society in a better way, and With a spiritual perspective, a scientist better appreciates the Creator, His creations and their mysteries. Thus, a quest for science and spirituality is always worth pursuing, and a proper understanding of both is essential for a harmony between the self, the society, the nation and the world.